The Safety Deposit Box is where you should store all of your valuable items. Random Events can result in an evil creature appearing and stealing one of your items, or even worse, turning it into a pile of sludge! By putting items in your safety deposit box, you're ensuring that your item won't get taken by a Random Event, sold in your shop, traded, or auctioned. Plus, if you get more than 1000 different items in your safety deposit box, you get a cool secret avatar :)
Your Safety Deposit Box comes with an account at the National Neopian Bank.